Tropocells® PRFM estar.tropocells 3 October 2024
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Tropocells® PRFM

(Platelet Rich Fibrin Matrix) is a fibrin gel matrix that is derived by combining Tropocells® PRP with autologous thrombin. Tropocells® TRS (Thrombin Rich Serum) is a major byproduct of Tropocells® PRF.

PRFM produced by PRP activation with TRS, provides a flexible platform that enables control of PRP concentration. Platelet concentration of at least one million/microliter is considered therapeutically effective. The platelet concentration affects the matrix viscosity and different growth factor release patterns. PRP activation with autologous thrombin shows an immediate release of PDGF and TGF that remains stable over time. VEGF demonstrates an increasing trend from 15 minutes up to 24 hours. PRFM platform enables also the control over the matrix diameter.

By combining Tropocells® TRS with Tropocells® PRP, physicians can obtain Growth Factors Rich Fibrin (GFRF) in the form of either injectable GFRF* or GFRF** membrane.

*GFRG -Growth Factors Rich Gel
**GFRF – Growth Factors Rich Fibrin

The Fibrin Matrix for Optimal Recovery
Why TropoCells® PRFM?
Tropocells® accelerates bone and soft tissue formation
  • Better stability of grafted tissue
  • Faster vascularization
  • Increases tissue generation due to growth factors release
  • Improves and hastens healing and regeneration; including epithelial wound healing – recovery is nearly 6 times faster
  • Jump starts osteogenesis
  • Faster preparation of implant site
Tropocells® seals the wound from infectious agents
  • Lower infection risk which helps to avoid further inflammation, complications, pain and post-operation discomfort
  • Decreased pre/post-operation bleeding
Tropocells® requires small amount of blood
  • Safe and convenience
  • No risk of rejection being an autologous material
Tropocells® PRP
Preparation
1
Collect whole blood directly into Tropocells® PRP tube

 PRFM Preparation step1

2
Centrifuge for 10 min, 1500g or 20 min (optional for more solid PRF)

PRFM Preparation step2

3
Insert the vented needle

 
4
Remove PPP fraction with 10ml syringe attached to a disc filter. Open the red grip stopper and use sterile forceps to remove PRF clot.

PRFM Preparation step4

5
Re-suspend the concentrated PRP with remaining plasma by a gentle inverting. Expel the PRF clot with forceps. Use the TRS fraction.

PRFM-Preparation-step5

6
Withdraw the concentrated PRP fraction, then the TRS fraction. Converge both TRS and PRP (in a ratio of 1:10 PRP:TRS) on a sterile dish to form PRFM. Apply the PRFM onto the desired tissue.

PRFM-Preparation-step6

How Tropocells® PRP is made

Patented Gel Separation Technology
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